1) "Resident Evil" Series (Except for "Gun Survivor")
2) "Super Metroid"
3) "Super Mario RPG"
4) "Metal Gear Solid" Series
5) "Saints Row"
6) "Dead Rising"
The last two will most likely change over time or so, but the top three are pretty much solid holders for some time to be. There's just too many games I love to play but not listing them is an injustice, which is why I stuck to console games only.
I've played "Nexus: The Jupiter Incident" and it's a bit complicated to get used to. All those ships started to lag my PC (Dual 3.0Ghz CPU, 256Mb nVidia, 1GIG RAM) and it was still stalling at times. Heard good reviews on it too, reason for getting it, the graphics are good close up, but a bit ratty when you pull out to check the whole area. I should give it another run again soon...
I also loved Gears of War, but I found it bit too short IMO, wish it would've been longer. The online multiplayer is probably worth it even more so, but I've always felt that console games need a solid single-player module to it, Halo achieved that with replay ability and boosted it with online use. GoW fell short on the former, and made it up with the latter, IMHO.
Loved Doom 3 too for the PC, great start and towards mid-way, but then it became *very* linear and repetitive. The graphics was great and the weapons rocked, but there was still a lack of a storyline and the levels were all the same, a common complaint. The beginning and the ending were the best of the game, the middle was the real Hell itself just getting through it to get till the end. Wanted to take the gun I was holding and shoot myself with it with the running in circles levels. RoE was a bit better, but gave you the most powerful weapon *EVER* right at the start of the game and made it just a bit too easy therefore.